WebMay 30, 2024 · Here we describe a simple yet robust determinant of developmental potential—the number of detectably expressed genes per cell— and leverage this measure of transcriptional diversity to develop a new framework for predicting ordered differentiation states from scRNA-seq data. When evaluated on ~150,000 single-cell transcriptomes … WebJun 30, 2024 · A predicted developmental order score of 1.0 is less differentiated, and a score of 0.0 is more. E = Embryonic-stage samples, as defined in [ 19 ], for this and all subsequent figures. ( B ) Box plots of the predicted ordering from CytoTRACE for all cells/embryos at the indicated stages, ordered by the mean developmental predicted …
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WebAug 25, 2024 · Big 12 predicted order of finish . Dennis Dodd Tom Fornelli Chip Patterson Barrett Sallee Ben Kercheval David Cobb ... WebOct 28, 2024 · An ordered trajectory across CAF phenotypes was inferred applying the CytoTRACE computational framework (Gulati et al., 2024) to cells with > 1000 unique genes. Selected genes related to CAF-activation ( FAP, ACTA2, S100A4 , IL6, IL1B, NNMT) and cell plasticity ( NT5E, ENO1, ITGB1, CD44, LGALS1, KIT) are presented as a smoothing spline … WebShading indicates inner (light gray) versus outer (dark gray) wound regions. (D) Box plots showing the predicted ordering by CytoTRACE for individual cells within the four scRNA … synthetic marijuana wax paper