Mcf10at1
Web17 jul. 2007 · MCF10AT1 cells were exposed for 20 passages with beta-HCH, 4-OH-Tamoxifen (Tam), or 17-beta-estradiol (E2) after which cells were analyzed for … WebOur study revealed that exposed MCF10AT1 cells developed, in a time-dependent manner, an acquired phenotype characterized by an increase in cancerous properties (anchorage independent growth and stem-like phenotype). Co-exposure of MCF10AT1 cells to B[a]P and BPA led to a significantly greater aggressive phenotype compared to B[a]P or BPA …
Mcf10at1
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Web3 jan. 2014 · We observed that mGluR1 is expressed in human breast cancer and that in MCF10A cells, which model nontransformed mammary epithelium, but not in MCF10AT1 … Web25 mei 2024 · Occurring in both MCF7 and MCF10AT1 cells, it suggests these actions of leptin to be independent of estrogen receptor status. By linking leptin signalling to the established TGFB1 pathway of metastasis / EMT, this study gives a direct mechanism by which leptin can contribute to the poorer outcomes of obese cancer patients.
Web3 jan. 2014 · MCF10AT1 cells, wild type or transduced with either LacZ or GRM1, were implanted into both flanks of athymic nude mice and allowed to grow for 8 weeks, after which MCF10AT1 lesions were harvested. A. Representative wild type MCF10AT1 lesion with both papillary enfolding (green arrow) and cribiform foci (red arrow). B. LacZ control … Web2 aug. 2024 · MCF10AT1-CRYβB2 tumors were less differentiated and resembled squamous cell carcinoma, while MCF10AT1-vector tumors were more differentiated and predominantly expressed features of adenocarcinoma ...
Web13 jan. 2024 · It is also unclear how common genetic defects, such as p53 mutations, modify these stromal-epithelial interactions. To address these knowledge gaps, we leveraged the MCF10 progression series of breast cell lines (MCF10A, MCF10AT1, and MCF10DCIS) to develop a longitudinal, tissue-contextualized model of p53-deficient, pre-malignant breast. Web1 jan. 2012 · The molecular mechanisms of breast cancer progression have been extensively studied using the MCF10 model. We summarized recent results on …
WebMCF10AT1 cells, wild type or transduced with either LacZ or GRM1, were implanted into both flanks of athymic nude mice and allowed to grow for 8 weeks, after which …
Web12 apr. 2024 · In contrast to MCF10A, treatment with E2 reduced MCF10AT1 shScramble viability by 10.5 ± 9.1% compared to MCF10AT1 + EtOH (p-value < 0.05; Figure 4G). Similar results were observed between MCF10AT1 sh62169 + E2 and MCF10AT1 sh62170 + E2 compared to their respective EtOH conditions; they were, nevertheless, statistically … the immigration and nationality act 1965WebNational Center for Biotechnology Information the immigration policy of the united statesWeb3 jun. 2016 · Methods Athymic nude mice were injected with MCF10AT1 cells in Matrigel® and fed a diet containing either 0.86 % methionine (control fed, CF), or 0.12 % methionine (MR) for 12 weeks. the immihelpWeb21 nov. 2016 · The non-malignant derivative line, MCF10AT1, is reported to be able to form tumours in immunocompromised mice, but does not metastasize 21. The malignant derivative line, ... the immigration process in americaWeb1 aug. 2009 · MCF10A (also referred as M1), a benign epithelial human cell line, and its metastatic mutant cell line counterpart MCF10CA1 (also referred as M4), were studied … the immigration shadow docketWeb3 jun. 2016 · Breast cancer cell lines MCF10A and MDA-MB-231 grown in methionine-restricted cysteine-depleted media for 24 h also up-regulated P21 and P27 gene … the immigration storyWebFor these studies, we used MCF10AT1 cells, a model for progressive breast cancer, injected into the mammary fatpad of nude mice as a single cell suspension. The mice were fed 0.1% sphingomyelin supplements in a semi-purified AIN76A control diet when the lesions were palpable. the immigration song led zeppelin lyrics